Long overdue Keytruda dose 21 update

Once upon a September and October, I began having a few strange symptoms with my Keytruda doses including weight gain that didn’t match my calorie intake, loss of pubic hair, some hot flashes. I mentioned them after discussing them with a nurse practitioner here. I had my estrogen levels tested and menopause was ruled out. Yay!

At my November appointment, my oncologist had taken a look at my symptoms and labs and diagnosed me with metabolic disorder. I certainly have a family history of these symptoms, although I don’t know if anyone in my family has actually discussed the overarching diagnosis of metabolic disorder with a doctor in the past.

My oncologist believes these symptoms are probably something that eventually would have been diagnosed with age, but the clinical trial medications or perhaps just the stress of this cancer journey have brought on the symptoms on a good 20 years early. Thankfully they are treatable and may not need medication but sweat therapy (aka exercise!)

It was after I finished with the doctor that my triglyceride levels came back from the lab and were high enough to rate a grade 3 adverse affect which meant I couldn’t get treatment that day. I came back the next day for fasting blood work which reduced my levels from 400 to 300, but not low enough to get me off the hook for a medication. I began meds and had beautiful blood work and dose 21 two weeks late on November 21st. It went without a hitch, thank God! Now I wait to see an endocrinologist to treat medication induced metabolic syndrome.

Decisions and Possible Surgery

Tomorrow afternoon Danny and I will meet with my oncology surgeon to discuss having my painful surface tumor(s) removed. We would appreciate prayers as we communicate with him and also hopefully will be able to talk to my main oncologist about our plan moving forward. We want to make sure that surgery doesn’t prevent my entering any trials nor do we want to delay further treatment and allow melanoma to gain footing while I recover from surgery. It does encourage us that both of my oncologists (surgical and melanoma specialist) feel that my disease is stable enough for me to take a treatment break to have this surgery. We believe removing these tumors will lessen my chronic pain and improve some quality of life issues. Please pray for wisdom and clarity for both of my doctors as well as Danny and me. Also, please pray that my main oncologist would be available to step in and consult with us during this appointment. I am so blessed to be treated at my clinic where the doctors work so closely together. Thank you all!